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- Fear as Homer
- Joy as Marge
- Russell (from Up) as Bart
- Riley as Lisa
- Sadness as Maggie
- Riley's Dad as Grandpa Abe
- Marlin (from Finding Nemo) as Krusty the Clown
- Emile (from Ratatouille) as Ned Flanders
- Riley's Mom as Maude Flanders
- Mater and Lightning McQueen (from Cars) as Lenny and Carl
- Carl Frederickson (from Up) as Moe
- Bing Bong as Barney
- Jangles the Clown as Mr. Burns
- Chet Alexander (from Monsters University) as Mr. Smithers
- Doc Hudson (from Cars) as Prinicpal Skinner
- Flo (from Cars) as Edna Krabappel
- Anger as Superintendent Chalmers
- Stinky Pete (from Toy Story 2) as Groundskeeper Willie
- Nemo (from Finding Nemo) as Milhouse
- Django (from Ratatouille) as Chief Wiggum
- The School of Moonfish (from Finding Nemo) as Mayor Quimby
- Charles Muntz (from Up) as Sideshow Bob
- Mor'Du (from Brave) as Johnny Tightlips
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